West and Gordon are called to the deserted mining town of Brimstone by a Professor Colecrest who has made a discovery of great importance. However, before they get to Brimstone, the Professor is captured by a gang of men also seeking his discovery. The professor, seriously injured in a fall, holds the key to the mystery, and Jim and Artie struggle to keep him alive until they can uncover the true root of the mystery.

Agent West raids a local warehouse in an attempt to apprehend a suspected opium gang member. As he struggles with the suspect, a new secret agent named Bosley Cranston rushes in and attempts to help. Unfortunately, he only makes matters worse, accidentally toppling a piano crate on the suspect and killing him. Cranston, however, is not the meek incompetent he appears and later surprises his colleagues with his karate skills and his popularity with beautiful women.

Agents West and Gordon have been investigating a series of explosions that have demolished several palatial homes. While they are guests of the wealthy Mr. Taney, they hear a high, whining sound. Suddenly the house begins to crumble and the agents escape in the nick of time to see a giant tuning fork radiating powerful sound waves. As they delve deeper into the case, they discover a letter to Mr. Taney from the Cyclops Insurance Company, urging him to take out a policy against further destruction of his property.

Agent West is summoned by a note from agent Gordon to the local barbershop. While waiting for Gordon, West decides to have a shave and is promptly anesthetised by a hot towel from one of Dr. Loveless's assistants, working in disguise. When he wakes up, he finds himself in a carnival funhouse where he encounters dazed-looking Justice Alonzo Fairlie. Before he can get any information from the judge, he is attacked by a quartet of gunmen. He quickly dispatches his adversaries but Justice Fairlie disappears in the confusion, leaving behined a strange clue.

West and Pike receive a note to meet a woman at a Chinese restaurant in San Francisco with a promise of information about the militant Din Chang who has recently stolen a supply of fulminate of mercury from a military arsenal. Unfortunately, the woman is killed before they can talk to her and the only word she utters is "Pelican". To further complicate matters, the only person they manage to capture is supposedly still serving time at Alcatraz. Since it seems that Alcatraz and the woman are the two pieces they have of the puzzle, the two split up to track down Chang before he can use the volatile mercury.

West and Gordon are called into Mexico to investigate a group of bandits who are attacking and terrorizing border towns. They track the bandits to a Mexican Village where the theives are hiding under the guise of an old Mexican legend about Cortez. Jim and Arte,not believing in the return of the god Cortez,are determined to find their way into the dorment volcano where the thugs are hiding.

After a series of disturbing incidents involving a raven that seems to hynoptize high-ranking officials into committing dastardly deeds,Agents West and Harper decide to find out what's going on. The incidents lead the new partners to a group calling themselves The Raven,led by Thaddeus Toombs and a man called Tycho (who has an enormous head and is very smart).

The plans of The Raven seem to be successful as they have hypnotized Jim West and had him assassinate the Mexican Ambassador. Unfortunately for the group,Frank Harper had been impersonating the ambassador to test whether Jim had been conditioned. West and Harper work together to infiltrate and undermine the group and capture everyone except for the huge-headed Tycho.

Jim meets with crime czar Sabatini, who asks him to travel to Calliope, MO to protect a lady and give a man called Swanson a key. Accompanied by government chemist Ned Brown, Jim travels to Calliope (where an Army finance officer died after stealing half a mil). Swanson is killed and the lady turns out to be Sabatini's ward blind Sylvia. It turns out Sabatini was the officer and Sylvia was the daughter of Boorman, Sabatini's partner in the robbery. Dodging Boorman, Jim and Ned find Sabatini's deed leaving all of his property to Sylvia.

A melody holds the clue West needs to trap a departmental traitor.

Gordon and West head to a lonely outpost to battle a terrorist gang.

West meets up with Gordon, who has just arrived in New Orleans with a famous Italian diva and niece of the ambassador on his arm, an escort urged by President Grant. West agrees to substitute as the lady's guardian for her appearance that evening at the opera, but the performance is interrupted when Montebello's would-be kidnappers bring down the curtain and West jumps into the fray. Discovering that sereral divas had recently disappeared in New Orleans, the agents must rush to unravel a plot involving the secret Order of Lucia and reveal who among their new acquaintances is playing a role on and off the stage.

West visits an eerie island to get a diamond for the National Museum.

West and Gordon are mixed up in the affairs of the royal family of Karovnia when they come to the US fleeing from assassins in their home country. The agents find that the evil Count Balkovitch is pursuing them, looking for an icon he needs to possess to hold power in Karovnia. Of course, the Count is not acting alone and the agents must discover who is assisting him before his dastardly plans are accomplished.

West deals with the kidnapping of the Governor's daughter while Gordon rushes to find Jim to inoculate him from the disease one of the criminals was carrying. The disease proves to be the turning point in the fight between the feds and the criminals as Gordon convinces the gang to turn themselves in exchange for the cure to the disease.

West becomes involved with the Jupiter Corporation after the director of the board and two others are killed. West exposes a deep plot by the late director's sister,Amelia,to dump stock,cause a panic,then make tons of money off of the cheap stock. West's investigation leads him to an odd bar with a cirus theme and animals who like to throw bombs. West uncovers Amelia's plan to kill off the rest of the board and is able to save the rest of the .